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CoNIFER 0.2.2 Beta

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CoNIFER offers the ability to mix exome sequence from multiple experimental runs by eliminating batch biases. Together with a short read aligner such as mrsFAST which can align reads to multiple locations, CoNIFER can robustly detect rare CNVs and estimate the copy number of duplicated genes up to ~8 copies with current exome capture kits. ...

Author Niklas Krumm
License Freeware
Price FREE
Released 2012-09-24
Downloads 230
Filesize 20 kB
Requirements
Installation Instal And Uninstall
Keywords sequence read, exome sequence, exome read, exome, sequence, genotype
Users' rating
(3 rating)
CoNIFERCADWindows XP, Windows Vista, Windows Vista x64, Windows 7, Windows 7 x64
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CoNIFER subject - Download Notice

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... of duplicated genes. As exome capture reactions are subject to strong and systematic capture biases between sample batches, we implemented singular value decomposition (SVD) to eliminate these biases in exome ...