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PedScope x64 is a standalone Windows and Mac application for advanced pedigree analysis, with applications in captive breeding programmes for endanged species conservation and safe breeding practices within closed or small populations such as pedigreed livestock, cats, dogs, etc.

Features

Computes various pedigree metrics including: Wright's coefficient of inbreeding; ancestral inbreeding coefficients; generation numbers; ancestry metrics including #generations seen, #generations full, #unique ancestors, etc.; relation counts such as #offspring, #sibs, etc.; age-related metrics including generational age, age at death, age at first child, etc. See: Pedigree Metrics.
Calculates various measures of genetic diversity including: the number of founder equivalents, the number of founder genome equivalents, and the effective number of ancestors, for any user-selected group of individuals that comprise a 'current population'. It can also perform detailed founder analyses for a group and report various details such as the proportion of genes present due to each founder, the genome uniqueness of each founder, and the percentage of each founders genes still present in the current population. It can also compute the mean kinship and kinship value for each individual within the group; metrics useful when making breeding recommendations aimed at retaining long term gene diversity within a population. See: Gene Diversity & Founder Analysis.
Makes breeding recommendations (i.e. mating recommendations) within a user-selected group of individuals. This is intended to let you compute the best matings in order to meet chosen breeding criteria, and is aimed primarily at those wanting to select matings to maximize future genetic diversity within the ongoing population. Criteria that can be used include: the inbreeding coefficient of the prospective offspring, the change in overall gene diversity ('GD delta') that would result from the mating, the change in overall gene value ('GV delta') that would result from the mating, parental mean kinships, parental kinship values, parental genome uniqueness, and any custom weighted combination of these. See: Breeding Recommendations.