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A comparative genomic tool: It assists biologists in analysing the genomic variations that correlate with pathogens, or the genomic changes that help microorganisms adapt in different environments. Sibelia x64 will also be helpful for the evolutionary and genome rearrangement studies for multiple strains of microorganisms.

Sibelia x64 is useful in finding: (1) shared regions, (2) regions that present in one group of genomes but not in others, (3) rearrangements that transform one genome to other genomes.

In version 2, Sibelia x64 works with multiple strains of bacteria and partitions their genomes into synteny blocks — blocks of highly conserved regions among all compared genomes. It represents genomes in circos pictures [for publication] or interactive forms [for experts’ analysis].

Sibelia x64 is under active development. If you see that Sibelia x64 has a potential to support your research, please do not hesitate to contact us at email.ru with a list of features you would like Sibelia x64 to have.